Preferred Label : cooperativity;
IUPAC definition : Interaction between the substrate binding sites of an allosteric enzyme. Binding of
a substrate molecule to one binding site changes the affinity of the binding sites
on the other subunits (cf. allosteric enzyme) to the substrate by induction of a conformation
change at the other binding sites. Cooperative enzymes typically display a sigmoid
(S-shaped) plot of the reaction rate against substrate concentration.;
Origin ID : C01325;
Automatic exact mappings (from CISMeF team)
- See also
Interaction between the substrate binding sites of an allosteric enzyme. Binding of
a substrate molecule to one binding site changes the affinity of the binding sites
on the other subunits (cf. allosteric enzyme) to the substrate by induction of a conformation
change at the other binding sites. Cooperative enzymes typically display a sigmoid
(S-shaped) plot of the reaction rate against substrate concentration.
