ICD-11 code : 4A85.00;
Preferred Label : Drug-induced liver hypersensitivity disease;
ICD-11 definition : Drug-induced liver hypersensitivity disease is a relatively rare condition, but can
have serious consequences for the individual patient, public health, regulatory agencies
and the pharmaceutical industry. It is characterized by elevation in serum alanine-aminotransferase
(ALT), conjugated bilirubin, or combined bilirubin, ALT and alkaline phosphatase (AP)
levels 2 times the upper limit of normal (ULN) and the most frequent related drugs
are halothane, tienilic acid, dihydralazine, diclofenac, and carbamazepine.;
ICD-11 synonym : Idiosyncratic drug-induced liver injury; medicament-induced liver hypersensitivity disease; Drug-induced liver injury; DILI - [Drug-induced liver injury];
ICD-11 acronym : DILI;
Origin ID : 674464254;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
Drug-induced liver hypersensitivity disease is a relatively rare condition, but can
have serious consequences for the individual patient, public health, regulatory agencies
and the pharmaceutical industry. It is characterized by elevation in serum alanine-aminotransferase
(ALT), conjugated bilirubin, or combined bilirubin, ALT and alkaline phosphatase (AP)
levels 2 times the upper limit of normal (ULN) and the most frequent related drugs
are halothane, tienilic acid, dihydralazine, diclofenac, and carbamazepine.
