ICD-11 code : DA01.21;
Preferred Label : Orofacial granulomatosis;
ICD-11 definition : Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterized
by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa
(the latter resulting in a cobblestone appearance), oral ulceration and the presence
on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn
disease, sometimes presenting months or years before bowel disease. Some cases are
associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous
cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with
fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).;
Origin ID : 239721777;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
Orofacial granulomatosis (OFG) is an uncommon clinicopathological entity characterized
by persistent and/or recurrent lymphoedema and fissuring of the lips and oral mucosa
(the latter resulting in a cobblestone appearance), oral ulceration and the presence
on biopsy of non-caseating granulomas. OFG may be an early manifestation of Crohn
disease, sometimes presenting months or years before bowel disease. Some cases are
associated with dental infections, sarcoidosis, food allergy or contact allergy. Granulomatous
cheilitis is a form of OFG confined to the lips. Rarely, OFG may be associated with
fissured tongue and facial palsy (Melkersson-Rosenthal syndrome).
