ICD-11 definition : Gestational pemphigoid (pemphigoid gestationis) is an autoimmune skin disease characterized
by pruritic plaques and blister formation on the skin in association with pregnancy
or the trophoblastic tumours, hydatiform mole and choriocarcinoma. The exact causes
of the disease are unknown but the disease is mediated by auto-antibodies to the hemidesmosome
component BP180/BPAg2/collagen XVII. The maternal antibodies may cause short lived
disease in the neonate, neonatal pemphigoid gestationis. This disease is not an infection
with herpes virus despite its old name, herpes gestationis.;
Gestational pemphigoid (pemphigoid gestationis) is an autoimmune skin disease characterized
by pruritic plaques and blister formation on the skin in association with pregnancy
or the trophoblastic tumours, hydatiform mole and choriocarcinoma. The exact causes
of the disease are unknown but the disease is mediated by auto-antibodies to the hemidesmosome
component BP180/BPAg2/collagen XVII. The maternal antibodies may cause short lived
disease in the neonate, neonatal pemphigoid gestationis. This disease is not an infection
with herpes virus despite its old name, herpes gestationis.