ICD-11 code : 1B20.20;
Preferred Label : Type I leprosy reaction;
ICD-11 definition : This phenomenon, also named upgrading reaction, occurs in borderline leprosy states
and is associated with an increase in cell-mediated immunity. It occurs typically
within the first 6 months of treatment in previously untreated patients but may be
related to stress, intercurrent infections, or pregnancy. Clinical features include
inflammatory swelling, erythema and occasionally ulceration of existing lesions, constitutional
symptoms and neuritis. If the neuritis is not treated promptly permanent motor nerve
damage may ensue.;
ICD-11 synonym : Leprosy reversal reaction; Leprosy upgrading reaction;
Origin ID : 1185467033;
UMLS CUI : C0343463;
CISMeF manual mappings
ICD-10 Mapping
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to NTBT
This phenomenon, also named upgrading reaction, occurs in borderline leprosy states
and is associated with an increase in cell-mediated immunity. It occurs typically
within the first 6 months of treatment in previously untreated patients but may be
related to stress, intercurrent infections, or pregnancy. Clinical features include
inflammatory swelling, erythema and occasionally ulceration of existing lesions, constitutional
symptoms and neuritis. If the neuritis is not treated promptly permanent motor nerve
damage may ensue.