ICD-11 code : EB90.10;
Preferred Label : Pretibial myxoedema;
ICD-11 definition : Pretibial myxoedema is a form of diffuse cutaneous mucinosis in which there is an
accumulation of excess glycosaminoglycans, especially hyaluronic acid, in the dermis
and subcutis. It is most commonly seen on the shins (pretibial areas) but does occur
elsewhere on the lower extremities. It manifests as violaceous or brownish, firm,
non-pitting, asymmetrical nodules or plaques or nodules which tend to coalesce to
produce extensive areas of induration with a peau d'orange (orange peel) appearance.
It is nearly always associated with autoimmune thyroiditis (Graves disease) and may
be associated with finger clubbing (acropachy) and exophthalmos (thyroid eye disease).;
Origin ID : 1002130466;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
ICD-10 Mapping
Pretibial myxoedema is a form of diffuse cutaneous mucinosis in which there is an
accumulation of excess glycosaminoglycans, especially hyaluronic acid, in the dermis
and subcutis. It is most commonly seen on the shins (pretibial areas) but does occur
elsewhere on the lower extremities. It manifests as violaceous or brownish, firm,
non-pitting, asymmetrical nodules or plaques or nodules which tend to coalesce to
produce extensive areas of induration with a peau d'orange (orange peel) appearance.
It is nearly always associated with autoimmune thyroiditis (Graves disease) and may
be associated with finger clubbing (acropachy) and exophthalmos (thyroid eye disease).