ICD-11 code : 5A60.0;
Preferred Label : Acromegaly or pituitary gigantism;
ICD-11 definition : Acromegaly is an acquired disorder related to excessive production of growth hormone
(GH) and characterized by progressive somatic disfigurement (mainly involving the
face and extremities) and systemic manifestations. The main clinical features are
broadened extremities (hands and feet), widened thickened and stubby fingers, and
thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory
and metabolic consequences which determine its prognosis. In the majority of cases,
acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or
mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails
to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or
radiotherapy can be used.;
ICD-11 inclusion : acromegalic arthritis; Marie disease; hypersomatotropic gigantism; growth hormone hypersecretion syndrome; Overproduction of growth hormone; acromegaly with arthropathy; acromegalic arthropathy; primordial giant; normal giant; giantism; gigantism; anterior pituitary adenoma syndrome; genetic giant; growth hormone hypersecretion; hypersomatotropism; acromegalia; Launois syndrome; acromegalic gigantism; giant; acromegaly; disorders with tall stature; hypophyseal gigantism; pituitary gigantism;
Origin ID : 825410563;
UMLS CUI : C0405578;
Currated CISMeF NLP mapping
- ICD-10 Mapping
- Semantic type(s)
- UMLS correspondences (same concept)
Acromegaly is an acquired disorder related to excessive production of growth hormone
(GH) and characterized by progressive somatic disfigurement (mainly involving the
face and extremities) and systemic manifestations. The main clinical features are
broadened extremities (hands and feet), widened thickened and stubby fingers, and
thickened soft tissue. The disease also has rheumatologic, cardiovascular, respiratory
and metabolic consequences which determine its prognosis. In the majority of cases,
acromegaly is related to a pituitary adenoma, either purely GH-secreting (60%) or
mixed. Transsphenoidal surgery is often the first-line treatment. When surgery fails
to correct GH/IGF-I hypersecretion, medical treatment with somatostatin analogs and/or
radiotherapy can be used.
