ICD-11 code : GA30.6;
Preferred Label : Premature ovarian failure;
ICD-11 definition : Menopause occurring spontaneously before 40 years of age, generally resulting in secondary
amenorrhea although some women may exhibit intermittent ovarian function and ovulation,
with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without
a known cause, but can be caused by the following conditions: numerical and structural
chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation
therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To
be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic
and unknown;
ICD-11 synonym : premature ovarian insufficiency; primary ovarian failure NOS; hypergonadotrophic ovarian failure; female hypergonadotropic hypogonadism; primary ovarian insufficiency; primary female hypogonadism; POF - [premature ovarian failure];
ICD-11 acronym : POF;
ICD-11 inclusion : insufficiency of ovary; hypofunction of ovary; ovarian failure; female hypogonadism syndrome; ovarian hypogonadism; ovary secretion deficiency; ovary hyposecretion; premature menopause NOS; decreased oestrogen; ovarian secretion suppression;
Origin ID : 756899519;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
ICD-10 Mapping
Menopause occurring spontaneously before 40 years of age, generally resulting in secondary
amenorrhea although some women may exhibit intermittent ovarian function and ovulation,
with a minority conceiving and delivering a pregnancy. POF/POI occurs mostly without
a known cause, but can be caused by the following conditions: numerical and structural
chromosomal abnormalities, Fragile X (FMR1) premutations, autoimmune disorders, radiation
therapy, chemotherapy, galactosemia, and other rare enzyme defects or mutations. To
be subdivided in 4 categories according to cause: congenital, acquired, iatrogenic
and unknown