ICD-11 code : 6C43.4;
Preferred Label : Opioid withdrawal;
ICD-11 definition : Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or
physiological features, varying in degree of severity and duration, that occurs upon
cessation or reduction of use of opioids in individuals who have developed Opioid
dependence or have used opioids for a prolonged period or in large amounts. Opioid
withdrawal can also occur when prescribed opioids have been used in standard therapeutic
doses. Presenting features of Opioid withdrawal may include dysphoric mood, craving
for an opioid, anxiety, nausea or vomiting, abdominal cramps, muscle aches, yawning,
perspiration, hot and cold flushes, lacrimation, rhinorrhea, hypersomnia (typically
in the initial phase) or insomnia, diarrhoea and piloerection.;
ICD-11 inclusion : heroin withdrawal; codeine withdrawal;
Origin ID : 663160065;
UMLS CUI : C0029104;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
Opioid withdrawal is a clinically significant cluster of symptoms, behaviours and/or
physiological features, varying in degree of severity and duration, that occurs upon
cessation or reduction of use of opioids in individuals who have developed Opioid
dependence or have used opioids for a prolonged period or in large amounts. Opioid
withdrawal can also occur when prescribed opioids have been used in standard therapeutic
doses. Presenting features of Opioid withdrawal may include dysphoric mood, craving
for an opioid, anxiety, nausea or vomiting, abdominal cramps, muscle aches, yawning,
perspiration, hot and cold flushes, lacrimation, rhinorrhea, hypersomnia (typically
in the initial phase) or insomnia, diarrhoea and piloerection.