ICD-11 code : 5A60.2;
Preferred Label : Syndrome of inappropriate secretion of antidiuretic hormone;
ICD-11 definition : Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterized
by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis.
Exact prevalence is unknown. The disease has been described in all age groups. SIADH
is often associated with tumors, pulmonary disease, central nervous system disorders
or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid
or pituitary insufficiency. The disorder is caused by gain-of-function mutations in
the gene encoding the vasopression V2 receptor. Fluid restriction is the most common
treatment. The outcome is related to the underlying and associated disorders.;
ICD-11 synonym : syndrome of inappropriate antidiuresis; antidiuretic hormone syndrome; inappropriate secretion of antidiuretic hormone; syndrome of inappropriate vasopressin secretion; hormone secretion; inadequate antidiuretic hormone secretion syndrome; Schwartz-Bartter syndrome; SIAD - [syndrome of inappropriate antidiuresis]; SIADH - [syndrome of inappropriate secretion of antidiuretic hormone]; Syndrome of inappropriate antidiuretic hormone secretion;
ICD-11 acronym : SIADH; SIAD;
ICD-11 inclusion : hypersecretion of antidiuretic hormone;
ICD-11 "other" category code : 5A60.2Y;
ICD-11 "unspecified" category code : 5A60.2Z;
Origin ID : 550787432;
UMLS CUI : C0021141;
Automatic exact mappings (from CISMeF team)
- SIADH [WHO-ART Preferred Term]
- Currated CISMeF NLP mapping
- ICD-10 Mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- SIADH [WHO-ART Preferred Term]
Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterized
by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis.
Exact prevalence is unknown. The disease has been described in all age groups. SIADH
is often associated with tumors, pulmonary disease, central nervous system disorders
or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid
or pituitary insufficiency. The disorder is caused by gain-of-function mutations in
the gene encoding the vasopression V2 receptor. Fluid restriction is the most common
treatment. The outcome is related to the underlying and associated disorders.
