ICD-11 code : 2E64.0;
Preferred Label : Intraepidermal squamous cell carcinoma;
ICD-11 definition : Malignant squamous neoplasia confined to the epidermis of extragenital skin and known
commonly as Bowen disease. It arises most frequently on chronically sun-exposed glabrous
skin of the head and neck or lower legs. It typically presents as single or multiple
well-demarcated scaly erythematous patches, nodules or plaques which histologically
show extensive keratinocytic atypia. It may develop from preexisting actinic keratosis
(Actinic intraepidermal squamous cell carcinoma). Although it is most commonly associated
with exposure to ultraviolet radiation, other carcinogens such as arsenic and tar
may be implicated. Human papilloma virus may represent an additional risk factor in
immunosuppressed patients.;
ICD-11 synonym : IEC - [intraepidermal carcinoma]; Squamous cell carcinoma in situ of skin; intraepidermal carcinoma;
ICD-11 acronym : IEC;
ICD-11 "other" category code : 2E64.0Y;
ICD-11 "unspecified" category code : 2E64.0Z;
Origin ID : 496229924;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
- Validated automatic mappings to BTNT
Malignant squamous neoplasia confined to the epidermis of extragenital skin and known
commonly as Bowen disease. It arises most frequently on chronically sun-exposed glabrous
skin of the head and neck or lower legs. It typically presents as single or multiple
well-demarcated scaly erythematous patches, nodules or plaques which histologically
show extensive keratinocytic atypia. It may develop from preexisting actinic keratosis
(Actinic intraepidermal squamous cell carcinoma). Although it is most commonly associated
with exposure to ultraviolet radiation, other carcinogens such as arsenic and tar
may be implicated. Human papilloma virus may represent an additional risk factor in
immunosuppressed patients.
