ICD-11 code : 2E64.0;
Preferred Label : Intraepidermal squamous cell carcinoma;
ICD-11 definition : It arises most frequently on chronically sun-exposed glabrous skin of the head and
neck or lower legs. It typically presents as single or multiple well-demarcated scaly
erythematous patches, nodules or plaques which histologically show extensive keratinocytic
atypia. It may develop from preexisting actinic keratosis (Actinic intraepidermal
squamous cell carcinoma). Although it is most commonly associated with exposure to
ultraviolet radiation, other carcinogens such as arsenic and tar may be implicated.
Human papilloma virus may represent an additional risk factor in immunosuppressed
patients.;
ICD-11 synonym : IEC - [intraepidermal carcinoma]; Squamous cell carcinoma in situ of skin; intraepidermal carcinoma;
ICD-11 acronym : IEC;
ICD-11 "other" category code : 2E64.0Y;
ICD-11 "unspecified" category code : 2E64.0Z;
Origin ID : 496229924;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
- Validated automatic mappings to BTNT
It arises most frequently on chronically sun-exposed glabrous skin of the head and
neck or lower legs. It typically presents as single or multiple well-demarcated scaly
erythematous patches, nodules or plaques which histologically show extensive keratinocytic
atypia. It may develop from preexisting actinic keratosis (Actinic intraepidermal
squamous cell carcinoma). Although it is most commonly associated with exposure to
ultraviolet radiation, other carcinogens such as arsenic and tar may be implicated.
Human papilloma virus may represent an additional risk factor in immunosuppressed
patients.
