ICD-11 code : CA26.1;
Preferred Label : Diffuse panbronchiolitis;
ICD-11 definition : Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease principally affecting
the respiratory bronchioles, causing a progressive suppurative and severe obstructive
respiratory disorder. Onset occurs in the second to fifth decade of life and manifests
by chronic cough, exertional dyspnea, and sputum production. Most patients also have
chronic paranasal sinusitis. If left untreated, DPB progresses to bronchiectasis,
respiratory failure and death. A significant improvement in the prognosis has been
reported thanks to the use of long-term therapy with macrolide antibiotics, the effect
of which is attributed to an anti-inflammatory and immunoregulatory action.;
Origin ID : 291357751;
Automatic exact mappings (from CISMeF team)
Diffuse panbronchiolitis (DPB) is an idiopathic inflammatory disease principally affecting
the respiratory bronchioles, causing a progressive suppurative and severe obstructive
respiratory disorder. Onset occurs in the second to fifth decade of life and manifests
by chronic cough, exertional dyspnea, and sputum production. Most patients also have
chronic paranasal sinusitis. If left untreated, DPB progresses to bronchiectasis,
respiratory failure and death. A significant improvement in the prognosis has been
reported thanks to the use of long-term therapy with macrolide antibiotics, the effect
of which is attributed to an anti-inflammatory and immunoregulatory action.
