ICD-11 code : GB55.0;
Preferred Label : Balkan nephropathy;
ICD-11 definition : Balkan nephropathy is a form of interstitial nephritis characterised by a very localised
geographic occurrence. It was first identified in the 1920s among several small, discrete
communities along the Danube River and its major tributaries. Now thought to be due
to chronic aristolochic acid ingestion (ingestion of Aristolochia clematitis seeds
native to the Balkan region), though it has some differences from Chinese herbal nephropathy.
This disease is characterised by renal insufficiency, proteinuria, tubulointerstitial
nephritis, anaemia, weakness, copper discoloration of the skin, and may lead to end-stage
renal disease within 5 years after onset.;
ICD-11 synonym : Balkan endemic nephropathy; Balkan nephritis;
ICD-11 inclusion : Balkan endemic nephropathy;
Origin ID : 18497836;
UMLS CUI : C0004698;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
ICD-10 Mapping
Semantic type(s)
UMLS correspondences (same concept)
Balkan nephropathy is a form of interstitial nephritis characterised by a very localised
geographic occurrence. It was first identified in the 1920s among several small, discrete
communities along the Danube River and its major tributaries. Now thought to be due
to chronic aristolochic acid ingestion (ingestion of Aristolochia clematitis seeds
native to the Balkan region), though it has some differences from Chinese herbal nephropathy.
This disease is characterised by renal insufficiency, proteinuria, tubulointerstitial
nephritis, anaemia, weakness, copper discoloration of the skin, and may lead to end-stage
renal disease within 5 years after onset.