ICD-11 code : 1E51.1;
Preferred Label : Chronic hepatitis C;
ICD-11 definition : A liver disease characterized by liver inflammation and fibrosis caused by more than
6 months of infection with the hepatitis C virus. Even at stage of cirrhosis there
may be no symptoms. Otherwise, clinical features include fatigue and impaired quality
of life, hard liver edge and complications of cirrhosis (muscle wasting, ascites,
splenomegaly/portal hypertension). Chronic hepatitis C increases the risks of type
2 diabetes mellitus and cardiovascular disease, which contribute to increased all-cause
mortality. Transmission is by blood and body fluid contamination, rarely by sexual
transmission and from mother to baby at the time of birth (vertical transmission).
Confirmation of the diagnosis is by detection of HCV RNA in the presence of a positive
anti-HCV in serum.;
ICD-11 synonym : hep C NOS; chronic HCV infection; hepatitis C infection NOS; chronic HCV - [hepatitis C virus] infection; hepatitis C NOS; hepatitis C-related cirrhosis; type C viral hepatitis; chronic type C viral hepatitis;
Origin ID : 1615937473;
UMLS CUI : C0524910;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
ICD-10 Mapping
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to NTBT
A liver disease characterized by liver inflammation and fibrosis caused by more than
6 months of infection with the hepatitis C virus. Even at stage of cirrhosis there
may be no symptoms. Otherwise, clinical features include fatigue and impaired quality
of life, hard liver edge and complications of cirrhosis (muscle wasting, ascites,
splenomegaly/portal hypertension). Chronic hepatitis C increases the risks of type
2 diabetes mellitus and cardiovascular disease, which contribute to increased all-cause
mortality. Transmission is by blood and body fluid contamination, rarely by sexual
transmission and from mother to baby at the time of birth (vertical transmission).
Confirmation of the diagnosis is by detection of HCV RNA in the presence of a positive
anti-HCV in serum.