ICD-11 code : 2A60.4;
Preferred Label : Myeloid proliferation associated with Down syndrome;
ICD-11 definition : Myeloid neoplasms occurring in individuals with Down syndrome. There is an increased
risk of acute leukaemias in both children and adults with Down syndrome. In particular,
the incidence of acute myeloid leukaemia in Down syndrome children of less than five
years of age is particularly high, it is usually an acute megakaryoblastic leukemia,
and is associated with GATA1 gene mutation. This group of disorders also includes
the entity transient abnormal myelopoiesis which occurs in neonates and is associated
with GATA1 gene mutation.;
ICD-11 "other" category code : 2A60.4Y;
ICD-11 "unspecified" category code : 2A60.4Z;
Origin ID : 1587058820;
Automatic exact mappings (from CISMeF team)
Myeloid neoplasms occurring in individuals with Down syndrome. There is an increased
risk of acute leukaemias in both children and adults with Down syndrome. In particular,
the incidence of acute myeloid leukaemia in Down syndrome children of less than five
years of age is particularly high, it is usually an acute megakaryoblastic leukemia,
and is associated with GATA1 gene mutation. This group of disorders also includes
the entity transient abnormal myelopoiesis which occurs in neonates and is associated
with GATA1 gene mutation.
