ICD-11 code : 5B90.0;
Preferred Label : Hypervitaminosis A;
ICD-11 definition : Because vitamin A is fat soluble and can be stored, primarily in the liver, routine
consumption of large amounts of vitamin A over a period of time can result in toxic
symptoms, including liver damage, bone abnormalities and joint pain, alopecia, headaches,
vomiting, and skin desquamation. Hypervitaminosis A appears to be due to abnormal
transport and distribution of vitamin A and retinoids caused by overloading of the
plasma transport mechanisms. Very high single doses can cause transient acute toxic
symptoms that may include bulging fontanelles in infants; headaches in older children
and adults; and vomiting, diarrhoea, loss of appetite, and irritability in all age
groups. Rarely does toxicity occur from ingestion of food sources of preformed vitamin
A. When this occurs, it usually results from very frequent consumption of liver products.;
ICD-11 synonym : hyperalimentation of Vitamin A;
ICD-11 inclusion : excess vitamin A administered as drug;
Origin ID : 1465667896;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
Because vitamin A is fat soluble and can be stored, primarily in the liver, routine
consumption of large amounts of vitamin A over a period of time can result in toxic
symptoms, including liver damage, bone abnormalities and joint pain, alopecia, headaches,
vomiting, and skin desquamation. Hypervitaminosis A appears to be due to abnormal
transport and distribution of vitamin A and retinoids caused by overloading of the
plasma transport mechanisms. Very high single doses can cause transient acute toxic
symptoms that may include bulging fontanelles in infants; headaches in older children
and adults; and vomiting, diarrhoea, loss of appetite, and irritability in all age
groups. Rarely does toxicity occur from ingestion of food sources of preformed vitamin
A. When this occurs, it usually results from very frequent consumption of liver products.
