ICD-11 code : FB82.3;
Preferred Label : Relapsing polychondritis;
ICD-11 definition : Relapsing polychondritis is a multisystem inflammatory disease of unknown etiology
affecting the cartilage. The disease is characterized by intermittent or fluctuant
inflammatory manifestations due to inflammation of the cartilaginous structures, resulting
in tissue damage and tissue destruction. Chondritis of auricular, nasal, tracheal
cartilage predominates in this disease, suggesting response to tissue-specific antigens
such as collagen II and cartilage matrix protein (matrillin-1). In about one third
of patients, RP is associated with vasculitis (from isolated cutaneous leucocytoclastic
vasculitis to systemic polyangiitis) and autoimmune rheumatic diseases (autoimmune
rheumatic diseases mainly rheumatoid arthritis and systemic lupus erythematosus).
Hematological malignant diseases, gastrointestinal disorders and endocrine diseases
may also occur. Functional and anatomical evaluation for upper and lower airway disease
is essential in evaluation and management of the disease.;
Origin ID : 1412888287;
UMLS CUI : C0032453;
Currated CISMeF NLP mapping
ICD-10 Mapping
Semantic type(s)
UMLS correspondences (same concept)
Relapsing polychondritis is a multisystem inflammatory disease of unknown etiology
affecting the cartilage. The disease is characterized by intermittent or fluctuant
inflammatory manifestations due to inflammation of the cartilaginous structures, resulting
in tissue damage and tissue destruction. Chondritis of auricular, nasal, tracheal
cartilage predominates in this disease, suggesting response to tissue-specific antigens
such as collagen II and cartilage matrix protein (matrillin-1). In about one third
of patients, RP is associated with vasculitis (from isolated cutaneous leucocytoclastic
vasculitis to systemic polyangiitis) and autoimmune rheumatic diseases (autoimmune
rheumatic diseases mainly rheumatoid arthritis and systemic lupus erythematosus).
Hematological malignant diseases, gastrointestinal disorders and endocrine diseases
may also occur. Functional and anatomical evaluation for upper and lower airway disease
is essential in evaluation and management of the disease.