ICD-11 code : 5B55.3;
Preferred Label : Vitamin A deficiency with corneal xerosis;
ICD-11 definition : Clinically, the cornea develops classical xerosis, a hazy, lustreless, dry appearance,
first apparent near the inferior limbus. Many children have characteristic superficial
punctate lesions of the inferior-nasal aspects of their cornea that stain brightly
with fluorescein. Early in the disease they are visible only through a slit-lamp examination.
With more severe disease the punctate lesions become more numerous and spread upwards
over the central cornea, and the corneal stroma becomes oedematous. Thick, keratinized
plaques resembling Bitot's spot may form on the corneal surface. These are often densest
in the interpalpebral zone. With treatment, these corneal plaques peel off, sometimes
leaving superficial erosion which quickly heals. Corneal xerosis responds within 2-5
days to vitamin A therapy, the cornea regaining its normal appearance in 1-2 weeks.;
ICD-11 synonym : Vitamin A deficiency with cornea xerosis;
Origin ID : 1307433024;
UMLS CUI : C0154233;
Currated CISMeF NLP mapping
- ICD-10 Mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
Clinically, the cornea develops classical xerosis, a hazy, lustreless, dry appearance,
first apparent near the inferior limbus. Many children have characteristic superficial
punctate lesions of the inferior-nasal aspects of their cornea that stain brightly
with fluorescein. Early in the disease they are visible only through a slit-lamp examination.
With more severe disease the punctate lesions become more numerous and spread upwards
over the central cornea, and the corneal stroma becomes oedematous. Thick, keratinized
plaques resembling Bitot's spot may form on the corneal surface. These are often densest
in the interpalpebral zone. With treatment, these corneal plaques peel off, sometimes
leaving superficial erosion which quickly heals. Corneal xerosis responds within 2-5
days to vitamin A therapy, the cornea regaining its normal appearance in 1-2 weeks.
