Preferred Label : Sporadic inclusion body myopathy;
ICD-11 definition : Sporadic inclusion body myositis is the most frequent acquired myopathy of middle
and later life and is distinguished from other inflammatory myopathies by its selective
pattern of muscle involvement and slowly progressive course, and by the combination
of inflammatory and degenerative muscle pathology and multi-protein deposits in muscle
tissue. Typical disease phenotype includes slowly progressive weakness and wasting
of the quadriceps and forearm muscles. A smaller group of patients present initially
because of weakness of the long finger flexor muscles or bulbar weakness, with lower
limb weakness occurring at a later stage.;
Origin ID : 983124715;
Automatic exact mappings (from CISMeF team)
Sporadic inclusion body myositis is the most frequent acquired myopathy of middle
and later life and is distinguished from other inflammatory myopathies by its selective
pattern of muscle involvement and slowly progressive course, and by the combination
of inflammatory and degenerative muscle pathology and multi-protein deposits in muscle
tissue. Typical disease phenotype includes slowly progressive weakness and wasting
of the quadriceps and forearm muscles. A smaller group of patients present initially
because of weakness of the long finger flexor muscles or bulbar weakness, with lower
limb weakness occurring at a later stage.
