ICD-11 definition : Diencephalic syndrome is characterized by a complex series of signs and symptoms related
to hypothalamic dysfunction. Its main features are emaciation, despite a normal or
slightly diminished calories intake, and an alert appearance. DS has been almost exclusively
described in association with space-occupying lesions of the hypothalamic-optic chiasma
region, mainly juvenile pilocytic astrocytoma.;
Diencephalic syndrome is characterized by a complex series of signs and symptoms related
to hypothalamic dysfunction. Its main features are emaciation, despite a normal or
slightly diminished calories intake, and an alert appearance. DS has been almost exclusively
described in association with space-occupying lesions of the hypothalamic-optic chiasma
region, mainly juvenile pilocytic astrocytoma.