" /> Late chronic graft-versus-host disease - CISMeF





Preferred Label : Late chronic graft-versus-host disease;

ICD-11 definition : Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterized by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability.;

ICD-11 synonym : Sclerodermatous chronic graft-versus-host disease; sclerodermatous GVHD - [graft-versus-host disease]; sclerodermatous GVHD; late chronic GVHD; late chronic GVHD - [graft-versus-host disease]; sclerodermatous graft-versus-host disease; graft-versus-host disease;

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Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterized by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability.

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29/05/2025


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