Preferred Label : Necrolytic migratory erythema;
ICD-11 definition : Necrolytic migratory erythema is a rare dermatosis closely associated with an underlying
glucagon-secreting tumour of pancreatic islet cells (glucagonoma). It may present
clinically with recent onset diabetes mellitus, weight loss and glossitis. Skin and
mucous membranes are affected with painful migratory erythematous polycyclic patches
or plaques with superficial pustules, vesicles, or bullae. The lesions are typically
widespread, but they are accentuated in the intertriginous areas, lower abdomen, and
proximal parts of the lower extremities. Lesions begin as erythematous papules; coalesce
into patches or plaques; evolve into vesicles, flaccid bullae, and pustules; and then
become eroded and crusted.;
ICD-11 inclusion : Glucagonoma syndrome;
Origin ID : 537557682;
Automatic exact mappings (from CISMeF team)
Necrolytic migratory erythema is a rare dermatosis closely associated with an underlying
glucagon-secreting tumour of pancreatic islet cells (glucagonoma). It may present
clinically with recent onset diabetes mellitus, weight loss and glossitis. Skin and
mucous membranes are affected with painful migratory erythematous polycyclic patches
or plaques with superficial pustules, vesicles, or bullae. The lesions are typically
widespread, but they are accentuated in the intertriginous areas, lower abdomen, and
proximal parts of the lower extremities. Lesions begin as erythematous papules; coalesce
into patches or plaques; evolve into vesicles, flaccid bullae, and pustules; and then
become eroded and crusted.
