Preferred Label : Bornavirus encephalitis;
ICD-11 definition : A subacute to acute and often fatal disease caused by infection with a bornavirus
as a result of spill-over transmission from an animal reservoir. Bornavirus encephalitis
begins with unspecific symptoms/signs (e.g., severe fatigue, weakness, headache, psychomotor
slowing) followed by progressively impaired locomotor functions, tetraparesis, sopor,
and coma. In most described cases the disease will lead to death several weeks after
the onset of symptoms. Lesions are typically characterized as non-purulent encephalitis.
The incubation period is unknown but considered to last weeks to months. The etiologic
viruses are restricted mainly to the central nervous system, absent in blood, and
viral shedding by humans has not been documented. There is no evidence of natural
person-to-person transmission, but iatrogenic transmission by solid organ transplantation
is possible.;
ICD-11 synonym : Borna disease;
Origin ID : 475104996;
UMLS CUI : C0006023;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
A subacute to acute and often fatal disease caused by infection with a bornavirus
as a result of spill-over transmission from an animal reservoir. Bornavirus encephalitis
begins with unspecific symptoms/signs (e.g., severe fatigue, weakness, headache, psychomotor
slowing) followed by progressively impaired locomotor functions, tetraparesis, sopor,
and coma. In most described cases the disease will lead to death several weeks after
the onset of symptoms. Lesions are typically characterized as non-purulent encephalitis.
The incubation period is unknown but considered to last weeks to months. The etiologic
viruses are restricted mainly to the central nervous system, absent in blood, and
viral shedding by humans has not been documented. There is no evidence of natural
person-to-person transmission, but iatrogenic transmission by solid organ transplantation
is possible.
