Preferred Label : Autoimmune encephalitis;
ICD-11 definition : Autoimmune encephalitis is an immune mediated inflammatory disorder of the central
nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly
short-term memory). A personal/family history of autoimmunity is typical and investigations
may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid.
Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies)
and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion
of alternative etiologies (e.g. infections) is important. Response to immunotherapy
may be used to confirm the diagnosis.;
ICD-11 synonym : Hashimoto's encephalitis; non-vasculitic autoimmune meningoencephalitis;
Origin ID : 241281019;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
Autoimmune encephalitis is an immune mediated inflammatory disorder of the central
nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly
short-term memory). A personal/family history of autoimmunity is typical and investigations
may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid.
Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies)
and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion
of alternative etiologies (e.g. infections) is important. Response to immunotherapy
may be used to confirm the diagnosis.
