ICD-11 definition : Familial prostate cancer is usually defined as the clustering of at least 2 first-
or second-degree relatives with prostate cancer within a family. Hereditary prostate
cancer is a subset of the familial forms and is usually defined as the familial clustering
of at least 3 first-degree relatives with the disease, or two relatives diagnosed
below the age of 55 years. These criteria must be extended to second-degree relatives
on the maternal side in order to include X-linked transmission of the disease.;
Familial prostate cancer is usually defined as the clustering of at least 2 first-
or second-degree relatives with prostate cancer within a family. Hereditary prostate
cancer is a subset of the familial forms and is usually defined as the familial clustering
of at least 3 first-degree relatives with the disease, or two relatives diagnosed
below the age of 55 years. These criteria must be extended to second-degree relatives
on the maternal side in order to include X-linked transmission of the disease.