Preferred Label : POEMS syndrome;
ICD-11 definition : POEMS syndrome is defined by the presence of a peripheral neuropathy (P), a monoclonal
plasma cell disorder (M), and other paraneoplastic features, the most common of which
are organomegaly (O), endocrinopathy (E), skin changes (S), papilledema, edema, effusions,
ascites, and thrombocytosis. Virtually all patients will have either at least one
sclerotic bone lesion or concomitant Castleman disease. Associated neural autoantibodies
are: Immunoglobulin G or Immunoglobulin A with lambda light chain, increased Vascular
endothelial growth factor.;
ICD-11 inclusion : Osteosclerotic myeloma;
Origin ID : 1555299114;
Currated CISMeF NLP mapping
POEMS syndrome is defined by the presence of a peripheral neuropathy (P), a monoclonal
plasma cell disorder (M), and other paraneoplastic features, the most common of which
are organomegaly (O), endocrinopathy (E), skin changes (S), papilledema, edema, effusions,
ascites, and thrombocytosis. Virtually all patients will have either at least one
sclerotic bone lesion or concomitant Castleman disease. Associated neural autoantibodies
are: Immunoglobulin G or Immunoglobulin A with lambda light chain, increased Vascular
endothelial growth factor.
