Preferred Label : Keratolytic winter erythema;
ICD-11 definition : Keratolytic winter erythema (MIM %148370) is an autosomal dominant disorder first
described in inhabitants of the province of Oudtshoorn in South Africa. It consists
in intermittent and recurrent centrifugal peeling and erythema of the palms and soles,
though it may extend up the limbs to the buttocks and the trunk. The age of onset
varies from infancy to early adulthood after which it tends to become less pronounced.
A striking feature is the onset and recurrence with cold winter weather. The genetic
basis is not understood as yet.;
ICD-11 synonym : Oudtshoorn disease;
ICD-11 inclusion : Oudtshoorn disease;
Origin ID : 1491245207;
Automatic exact mappings (from CISMeF team)
Keratolytic winter erythema (MIM %148370) is an autosomal dominant disorder first
described in inhabitants of the province of Oudtshoorn in South Africa. It consists
in intermittent and recurrent centrifugal peeling and erythema of the palms and soles,
though it may extend up the limbs to the buttocks and the trunk. The age of onset
varies from infancy to early adulthood after which it tends to become less pronounced.
A striking feature is the onset and recurrence with cold winter weather. The genetic
basis is not understood as yet.
