Preferred Label : Gorham-Stout disease;
ICD-11 definition : Gorham-Stout disease is defined as a spontaneous, massive osteolysis characterized
by local proliferation of small vascular or lymphatic vessels resulting in progressive
destruction and resorption of bone. Clinical signs at presentation include pain, swelling
and spontaneous fractures. Osteolysis may stop progressing at any time, but often
osseous tissue completely disappears, leaving only a residual fibrous band, a dramatic
development inspiring the term 'vanishing bone disease.';
ICD-11 synonym : Gorham massive osteolysis;
Origin ID : 1318015458;
Automatic exact mappings (from CISMeF team)
Gorham-Stout disease is defined as a spontaneous, massive osteolysis characterized
by local proliferation of small vascular or lymphatic vessels resulting in progressive
destruction and resorption of bone. Clinical signs at presentation include pain, swelling
and spontaneous fractures. Osteolysis may stop progressing at any time, but often
osseous tissue completely disappears, leaving only a residual fibrous band, a dramatic
development inspiring the term 'vanishing bone disease.'
