Preferred Label : Ankylosing vertebral hyperostosis with tylosis;
ICD-11 definition : This syndrome is characterized by the association of ankylosing vertebral hyperostosis
with hyperkeratosis of the soles and palms. It has been described in at least eight
patients, in four sibships spanning two generations of a Greek-Cypriot family. Six
other members of the family presented with palmoplantar hyperkeratosis alone. This
syndrome is likely to be transmitted as an autosomal dominant trait. It is distinct
from diffuse idiopathic skeletal hyperostosis (DISH) which is not a rare disease.;
Origin ID : 120916486;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
This syndrome is characterized by the association of ankylosing vertebral hyperostosis
with hyperkeratosis of the soles and palms. It has been described in at least eight
patients, in four sibships spanning two generations of a Greek-Cypriot family. Six
other members of the family presented with palmoplantar hyperkeratosis alone. This
syndrome is likely to be transmitted as an autosomal dominant trait. It is distinct
from diffuse idiopathic skeletal hyperostosis (DISH) which is not a rare disease.
