ICD-11 definition : This disorder involves involuntary muscle contractions, tremors, and other uncontrolled
movements (dystonia). Patients often have diurnal fluctuations with worsening in the
afternoon and improvement in the morning. Parikinsonism may occur in older individuals
in the family. It is inherited in an autosomal dominant fashion and is often responsive
to treatment with L-Dopa.Also called Segawa Disease. It is due to a mutation in the
GTP Cyclohydrolase gene.;
This disorder involves involuntary muscle contractions, tremors, and other uncontrolled
movements (dystonia). Patients often have diurnal fluctuations with worsening in the
afternoon and improvement in the morning. Parikinsonism may occur in older individuals
in the family. It is inherited in an autosomal dominant fashion and is often responsive
to treatment with L-Dopa.Also called Segawa Disease. It is due to a mutation in the
GTP Cyclohydrolase gene.