Preferred Label : Tertiary hyperparathyroidism;
ICD-11 definition : Tertiary hyperparathyroidism develops in some patients with advanced renal failure
and some other rare diseases, such as X-linked hypophosphatemic rickets/osteomalacia,
and they present hypercalcemia due to progression from appropriate parathyroid hyperplasia
to autonomous overproduction of PTH. If the patient with end-stage renal disease undergoes
renal transplantation, the parathyroid gland hyperplasia subsides over a period of
months to years. In some patients, hypercalcemia may develop after renal transplantation,
because correction of the renal failure normalizes phosphate balance and increases
calcitriol production, thereby raising serum calcium concentrations transiently until
the parathyroid hyperplasia subsides. In some cases, parathyroid hyperplasia may not
resolve completely.;
Origin ID : 10683191;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
Tertiary hyperparathyroidism develops in some patients with advanced renal failure
and some other rare diseases, such as X-linked hypophosphatemic rickets/osteomalacia,
and they present hypercalcemia due to progression from appropriate parathyroid hyperplasia
to autonomous overproduction of PTH. If the patient with end-stage renal disease undergoes
renal transplantation, the parathyroid gland hyperplasia subsides over a period of
months to years. In some patients, hypercalcemia may develop after renal transplantation,
because correction of the renal failure normalizes phosphate balance and increases
calcitriol production, thereby raising serum calcium concentrations transiently until
the parathyroid hyperplasia subsides. In some cases, parathyroid hyperplasia may not
resolve completely.
