Preferred Label : Fetal Valproate Spectrum Disorder;
ICD-11 definition : Fetal valproate syndrome is a fetopathy likely to occur when a pregnant woman takes
valproic acid/valproate for epileptic seizures. For women treated with valproic acid
during the first trimester of their pregnancy the risk of giving birth to infants
with spina bifida is 30 higher than that for the general population. Other teratogenic
effects specific to valproic acid are: hypospadias, malformations of the thumb and
hallux, and a dysmorphic syndrome called foetal valproate syndrome.;
Origin ID : 1055155432;
- Currated CISMeF NLP mapping
Fetal valproate syndrome is a fetopathy likely to occur when a pregnant woman takes
valproic acid/valproate for epileptic seizures. For women treated with valproic acid
during the first trimester of their pregnancy the risk of giving birth to infants
with spina bifida is 30 higher than that for the general population. Other teratogenic
effects specific to valproic acid are: hypospadias, malformations of the thumb and
hallux, and a dysmorphic syndrome called foetal valproate syndrome.