ICD-11 definition : Follicular lymphoma (FL) is a neoplasm composed of follicle centre (germinal centre)
B-cells (typically both centrocytes and centroblasts/large transformed cells), which
usually has at least a partially follicular pattern. t(14;18) with BCL2 rearrangement
is frequently observed. If diffuse areas of any size comprised predominantly or entirely
of blastic cells are present in any case of follicular lymphoma, a diagnosis of diffuse
large B-cell lymphoma is also made. Lymphomas composed of centro cytes and centroblasts
with an entirely diffuse pattern in the sampled tissue may be included in this category.;
Follicular lymphoma (FL) is a neoplasm composed of follicle centre (germinal centre)
B-cells (typically both centrocytes and centroblasts/large transformed cells), which
usually has at least a partially follicular pattern. t(14;18) with BCL2 rearrangement
is frequently observed. If diffuse areas of any size comprised predominantly or entirely
of blastic cells are present in any case of follicular lymphoma, a diagnosis of diffuse
large B-cell lymphoma is also made. Lymphomas composed of centro cytes and centroblasts
with an entirely diffuse pattern in the sampled tissue may be included in this category.