ICD-11 code : 8C62;
Preferred Label : Lambert-Eaton syndrome;
ICD-11 definition : Lambert-Eaton myasthenic syndrome, 20 times as rare as Acetylcholine receptor positive
Myasthenia gravis with a prevalence of 3.42 per million, is an immune-mediated disease
of the neuromuscular junction. Clinically the disease is characterized by proximal
weakness of the legs. In most patients, the weakness extends to other muscles including
the oculobulbar ones. Autonomic symptoms (dry mouth, erectile dysfunction, constipation)
are frequent. Tendon reflexes are reduced. Repetitive nerve stimulation shows low
Compound muscle action potentials, decrement 10% al low frequency and increment
100% after maximum voluntary contraction at high frequency.;
ICD-11 synonym : Lambert-Eaton myasthenic syndrome; Eaton-Lambert syndrome; LEMS - [Lambert-Eaton myasthenic syndrome];
ICD-11 acronym : LEMS;
Origin ID : 796417193;
UMLS CUI : C0022972;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
- Semantic type(s)
- UMLS correspondences (same concept)
Lambert-Eaton myasthenic syndrome, 20 times as rare as Acetylcholine receptor positive
Myasthenia gravis with a prevalence of 3.42 per million, is an immune-mediated disease
of the neuromuscular junction. Clinically the disease is characterized by proximal
weakness of the legs. In most patients, the weakness extends to other muscles including
the oculobulbar ones. Autonomic symptoms (dry mouth, erectile dysfunction, constipation)
are frequent. Tendon reflexes are reduced. Repetitive nerve stimulation shows low
Compound muscle action potentials, decrement 10% al low frequency and increment
100% after maximum voluntary contraction at high frequency.
