ICD-11 code : 2B6B;
Preferred Label : Malignant neoplasms of nasopharynx;
ICD-11 definition : A wide variety of tumours can arise in the nasopharynx, but it is nasopharyngeal carcinoma
that has fascinated generations of oncologists, pathologists, scientists and epidemiologists.
It shows marked geographic differences, with highest incidence rates in Southern Chinese.
In some endemic areas, the incidence has declined by about 30% over the past two decades,
suggesting that environmental or lifestyle factors may play a major role and that
the disease is, to some extent, preventable. Nasopharyngeal carcinoma shows a very
strong association with Epstein-Barr virus (EBV) infection, irrespective of the ethnic
origin of the patients. This association has pioneered a new paradigm of utilizing
viral serological tests for the diagnosis of cancer and for screening in high-risk
populations. Naso -pharyngeal carcinoma is generally responsive to radiation therapy,
and the clinical outcome has greatly improved over the years, due to refinements in
staging and to improved therapy protocols. The unusual and often deceptive histological
features of nasopharyngeal carcinoma have generated controversies over the nature
of the tumour and still pose a challenge to surgical pathologists. There have possibly
been more names invented for the various histological subtypes of nasopharyngeal carcinoma
than any other tumour type.;
ICD-11 synonym : malignant neoplasm of pharyngeal recess; malignant neoplasm of fossa of Rosenmüller; malignant neoplasm of anterior wall of nasopharynx; malignant tumor of epipharynx; malignant neoplasm of posterior margin of nasal septum; malignant neoplasm of opening of auditory tube; primary malignant neoplasm of lateral wall of nasopharynx; primary malignant neoplasm of superior wall of nasopharynx; nasopharyngeal cancer; primary malignant neoplasm of posterior wall of nasopharynx; malignant neoplasm of posterior margin of nasal choana; malignant neoplasm of anterior or posterior surface of nasopharyngeal soft palate; malignant neoplasm of floor of nasopharynx; malignant tumor of anterior wall of nasopharynx; malignant neoplasm of roof of nasopharynx; malignant tumor of postnasal space; malignant neoplasm of nasopharyngeal wall NOS;
ICD-11 "other" category code : 2B6B.Y;
ICD-11 "unspecified" category code : 2B6B.Z;
Origin ID : 547578362;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
A wide variety of tumours can arise in the nasopharynx, but it is nasopharyngeal carcinoma
that has fascinated generations of oncologists, pathologists, scientists and epidemiologists.
It shows marked geographic differences, with highest incidence rates in Southern Chinese.
In some endemic areas, the incidence has declined by about 30% over the past two decades,
suggesting that environmental or lifestyle factors may play a major role and that
the disease is, to some extent, preventable. Nasopharyngeal carcinoma shows a very
strong association with Epstein-Barr virus (EBV) infection, irrespective of the ethnic
origin of the patients. This association has pioneered a new paradigm of utilizing
viral serological tests for the diagnosis of cancer and for screening in high-risk
populations. Naso -pharyngeal carcinoma is generally responsive to radiation therapy,
and the clinical outcome has greatly improved over the years, due to refinements in
staging and to improved therapy protocols. The unusual and often deceptive histological
features of nasopharyngeal carcinoma have generated controversies over the nature
of the tumour and still pose a challenge to surgical pathologists. There have possibly
been more names invented for the various histological subtypes of nasopharyngeal carcinoma
than any other tumour type.
