ICD-11 code : 2B68;
Preferred Label : Malignant neoplasms of submandibular or sublingual glands;
ICD-11 definition : Salivary gland tumours can show a striking range of morphological diversity between
different tumour types and sometimes within an individual tumour mass. In addition,
hybrid tumours, dedifferentiation and the propensity for some benign tumours to progress
to malignancy can confound histopathological interpretation. These features, together
with the relative rarity of a number of tumours, can sometimes make diagnosis difficult,
despite the abundance of named tumour entities. The increasing use of pre-operative
fine needle aspiration biopsies also needs to be taken into account, as artifactual
changes may be superimposed on the tumours. Unfortunately, the morphological variability
of these tumours is mirrored by the immunocytochemical profiles, so that special stains
are rarely useful in routine diagnosis of salivary gland epithelial neoplasms.;
ICD-11 synonym : malignant neoplasm of submaxillary gland; malignant neoplasm of major salivary gland NOS; submandibular gland cancer;
ICD-11 "unspecified" category code : 2B68.Z;
Origin ID : 480928417;
UMLS CUI : C1306048;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
ICD-10 Mapping
Semantic type(s)
UMLS correspondences (same concept)
Salivary gland tumours can show a striking range of morphological diversity between
different tumour types and sometimes within an individual tumour mass. In addition,
hybrid tumours, dedifferentiation and the propensity for some benign tumours to progress
to malignancy can confound histopathological interpretation. These features, together
with the relative rarity of a number of tumours, can sometimes make diagnosis difficult,
despite the abundance of named tumour entities. The increasing use of pre-operative
fine needle aspiration biopsies also needs to be taken into account, as artifactual
changes may be superimposed on the tumours. Unfortunately, the morphological variability
of these tumours is mirrored by the immunocytochemical profiles, so that special stains
are rarely useful in routine diagnosis of salivary gland epithelial neoplasms.