ICD-11 code : 5B5E;
Preferred Label : Folate deficiency;
ICD-11 definition : Nutritional deficiency of folate is common in people consuming a limited diet. This
can be exacerbated by malabsorption conditions, including coeliac disease and tropical
sprue. Pregnant women are at risk for folate deficiency because pregnancy significantly
increases the folate requirement, especially during periods of rapid fetal growth
(i.e. in the second and third trimester). During lactation, losses of folate in milk
also increase the folate requirement. During pregnancy, there is an increased risk
of fetal neural tube defects (NTDs), with risk increasing 10-fold as folate status
goes from adequate to poor. Between days 21 and 27 post-conception, the neural plate
closes to form what will eventually be the spinal cord and cranium. Spina bifida,
anencephaly, and other similar conditions are collectively called NTDs. They result
from improper closure of the spinal cord and cranium, respectively, and are the most
common congenital abnormalities associated with folate deficiency.;
ICD-11 synonym : folic acid deficiency;
Origin ID : 439233336;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
Nutritional deficiency of folate is common in people consuming a limited diet. This
can be exacerbated by malabsorption conditions, including coeliac disease and tropical
sprue. Pregnant women are at risk for folate deficiency because pregnancy significantly
increases the folate requirement, especially during periods of rapid fetal growth
(i.e. in the second and third trimester). During lactation, losses of folate in milk
also increase the folate requirement. During pregnancy, there is an increased risk
of fetal neural tube defects (NTDs), with risk increasing 10-fold as folate status
goes from adequate to poor. Between days 21 and 27 post-conception, the neural plate
closes to form what will eventually be the spinal cord and cranium. Spina bifida,
anencephaly, and other similar conditions are collectively called NTDs. They result
from improper closure of the spinal cord and cranium, respectively, and are the most
common congenital abnormalities associated with folate deficiency.
