ICD-11 code : GB50;
Preferred Label : Acute tubulo-interstitial nephritis;
ICD-11 definition : A disease characterized by acute inflammation of, and damage to, tubules and the interstitium
of the kidney, usually accompanied by acute renal failure (acute kidney injury). Histology
shows acute inflammatory infiltrate in the interstitium with oedema and tubular cell
necrosis, and often prominent eosinophils and plasma cells. Usually due to an allergic
or immunological reaction to an identifiable allergen. Usually accompanied by acute
renal failure which may be reversible if the allergen is withdrawn expeditiously with
or without corticosteroid administration. Can lead to chronic tubulointerstitial nephritis,
particularly if the allergen exposure is not short term. May be associated with other
signs of an allergic reaction such as rash or fever.;
ICD-11 synonym : AIN - [acute interstitial nephritis]; acute tubulointerstitial disease; ATIN - [acute tubulo-interstitial nephritis]; acute interstitial nephritis;
ICD-11 acronym : AIN; ATIN;
ICD-11 inclusion : Acute infectious interstitial nephritis; acute infectious tubulo-interstitial nephritis; acute TIN - [acute tubulointerstitial nephritis];
Origin ID : 370349933;
UMLS CUI : C0149937;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
False automatic mappings
ICD-10 Mapping
Semantic type(s)
UMLS correspondences (same concept)
A disease characterized by acute inflammation of, and damage to, tubules and the interstitium
of the kidney, usually accompanied by acute renal failure (acute kidney injury). Histology
shows acute inflammatory infiltrate in the interstitium with oedema and tubular cell
necrosis, and often prominent eosinophils and plasma cells. Usually due to an allergic
or immunological reaction to an identifiable allergen. Usually accompanied by acute
renal failure which may be reversible if the allergen is withdrawn expeditiously with
or without corticosteroid administration. Can lead to chronic tubulointerstitial nephritis,
particularly if the allergen exposure is not short term. May be associated with other
signs of an allergic reaction such as rash or fever.