ICD-11 code : 8C02;
Preferred Label : Toxic neuropathy;
ICD-11 definition : In considering the diagnosis of toxic neuropathy, two criteria should be met: (1)
Exposure can be verified and temporally related to the onset of clinical symptoms.
Neuropathic symptoms usually occur concurrently with the exposure or following a variable
latency of up to several months. (2) There must be neurological signs and abnormal
electrodiagnostic studies, because many toxic neuropathies are subclinical, subjective
symptoms may or may not occur. Removal from exposure results in cessation of progression
of symptoms and the deficit. Most toxins produce symmetrical axonal degeneration in
a length-dependent pattern, beginning in the distal segments of the long and large-calibre
nerve fibres eventually spreading proximally with continued exposure. In addition
to motor and /or sensory deficits, severe pain may be a characteristic feature.;
ICD-11 synonym : Toxic polyneuropathy;
ICD-11 "other" category code : 8C02.Y;
ICD-11 "unspecified" category code : 8C02.Z;
Origin ID : 316350069;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
In considering the diagnosis of toxic neuropathy, two criteria should be met: (1)
Exposure can be verified and temporally related to the onset of clinical symptoms.
Neuropathic symptoms usually occur concurrently with the exposure or following a variable
latency of up to several months. (2) There must be neurological signs and abnormal
electrodiagnostic studies, because many toxic neuropathies are subclinical, subjective
symptoms may or may not occur. Removal from exposure results in cessation of progression
of symptoms and the deficit. Most toxins produce symmetrical axonal degeneration in
a length-dependent pattern, beginning in the distal segments of the long and large-calibre
nerve fibres eventually spreading proximally with continued exposure. In addition
to motor and /or sensory deficits, severe pain may be a characteristic feature.
