ICD-11 definition : Dermatitis herpetiformis is an immunobullous skin characterized by recurrent eruptions
of intensely itchy papules, vesicles or bullae, which are typically grouped symmetrically
on the extensor surfaces of the limbs and on the buttocks and back. The primary lesions
are frequently obscured by excoriation. An incompletely understood abnormal response
to dietary gluten provokes the formation of autoantibodies to tissue and epidermal
transglutaminases and granular deposition of IgA in dermal papillae. The disease is
strongly associated with gluten-sensitive enteropathy, which can range from mild jejunal
epithelial inflammation to total villous atrophy (coeliac disease).;
Dermatitis herpetiformis is an immunobullous skin characterized by recurrent eruptions
of intensely itchy papules, vesicles or bullae, which are typically grouped symmetrically
on the extensor surfaces of the limbs and on the buttocks and back. The primary lesions
are frequently obscured by excoriation. An incompletely understood abnormal response
to dietary gluten provokes the formation of autoantibodies to tissue and epidermal
transglutaminases and granular deposition of IgA in dermal papillae. The disease is
strongly associated with gluten-sensitive enteropathy, which can range from mild jejunal
epithelial inflammation to total villous atrophy (coeliac disease).