ICD-11 definition : Pemphigus is a group of chronic autoimmune skin diseases characterized by blister
formation on the skin and the mucous membranes. The exact causes of the disease are
unknown but the disease is mediated by auto-antibodies to desmosome components. Three
clinical forms have been characterised. Pemphigus vulgaris, pemphigus foliaceus and
pemphigus vegetans. Other variants exist, namely intercellular IgA dermatosis and
paraneoplastic pemphigus.;
Pemphigus is a group of chronic autoimmune skin diseases characterized by blister
formation on the skin and the mucous membranes. The exact causes of the disease are
unknown but the disease is mediated by auto-antibodies to desmosome components. Three
clinical forms have been characterised. Pemphigus vulgaris, pemphigus foliaceus and
pemphigus vegetans. Other variants exist, namely intercellular IgA dermatosis and
paraneoplastic pemphigus.