ICD-11 code : 2D11;
Preferred Label : Malignant neoplasms of adrenal gland;
ICD-11 definition : Tumours arising from the adrenal cortex include adenomas and carcinomas. These are
rare neoplasms but may cause a variety of hormonal symptoms, including hyperaldosteronism,
Cushing syndrome, and virilisation. A small fraction of adrenocortical tumours are
associated with an inherited tumour syndrome, including Li-Fraumeni syndrome and Carney
complex. Benign and malignant phaeochromocytomas arise in the adrenal medulla and
are derived from chromaffin cells of neural crest origin. Phaeochromocytomas may occur
in the setting of several hereditary conditions, including multiple endocrine neoplasia
types 2a and 2b, von Hippel Lindau disease and neurofibromatosis. Extra adrenal paragangliomas
arise from chromaffin cells in sympathoadrenal and parasympathetic paraganglia. They
occur in many parts of the body and can pose a significant challenge to surgeons and
oncologists. Some function as chemoreceptors, others are endocrinologically active.
Familial paragangliomas are associated with mutations of the mitochondrial complex
II genes.;
ICD-11 synonym : malignant tumor of adrenal gland; suprarenal gland cancer; malignant neoplasm of adrenal gland, unspecified; suprarenal cancer; adrenal cancer; malignant neoplasm of suprarenal gland; primary malignant neoplasm of adrenal gland; adrenal gland malignancy; adrenal gland cancer;
ICD-11 "other" category code : 2D11.Y;
ICD-11 "unspecified" category code : 2D11.Z;
Origin ID : 1766185236;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
Tumours arising from the adrenal cortex include adenomas and carcinomas. These are
rare neoplasms but may cause a variety of hormonal symptoms, including hyperaldosteronism,
Cushing syndrome, and virilisation. A small fraction of adrenocortical tumours are
associated with an inherited tumour syndrome, including Li-Fraumeni syndrome and Carney
complex. Benign and malignant phaeochromocytomas arise in the adrenal medulla and
are derived from chromaffin cells of neural crest origin. Phaeochromocytomas may occur
in the setting of several hereditary conditions, including multiple endocrine neoplasia
types 2a and 2b, von Hippel Lindau disease and neurofibromatosis. Extra adrenal paragangliomas
arise from chromaffin cells in sympathoadrenal and parasympathetic paraganglia. They
occur in many parts of the body and can pose a significant challenge to surgeons and
oncologists. Some function as chemoreceptors, others are endocrinologically active.
Familial paragangliomas are associated with mutations of the mitochondrial complex
II genes.
