Crimean-Congo haemorrhagic fever

ICD-11 code : 1D49;

Preferred Label : Crimean-Congo haemorrhagic fever;

ICD-11 definition : A disease caused by an infection with Crimean-Congo haemorrhagic fever virus. The length of the incubation period depends on the mode of acquisition of the virus. Following infection by a tick bite, the incubation period is usually one to three days, with a maximum of nine days. The incubation period following contact with infected blood or tissues is usually five to six days, with a documented maximum of 13 days. Onset of symptoms is sudden, with fever, myalgia, (muscle ache), dizziness, neck pain and stiffness, backache, headache, sore eyes and photophobia (sensitivity to light). There may be nausea, vomiting, diarrhoea, abdominal pain and sore throat early on, followed by sharp mood swings and confusion. After two to four days, the agitation may be replaced by sleepiness, depression and lassitude, and the abdominal pain may localize to the upper right quadrant, with detectable hepatomegaly (liver enlargement). Other clinical signs include tachycardia (fast heart rate), lymphadenopathy (enlarged lymph nodes), and a petechial rash (a rash caused by bleeding into the skin) on internal mucosal surfaces, such as in the mouth and throat, and on the skin. The petechiae may give way to larger rashes called ecchymoses, and other haemorrhagic phenomena. There is usually evidence of hepatitis, and severely ill patients may experience rapid kidney deterioration, sudden liver failure or pulmonary failure after the fifth day of illness. The mortality rate from CCHF is approximately 30%, with death occurring in the second week of illness. In patients who recover, improvement generally begins on the ninth or tenth day after the onset of illness. The CCHF virus is transmitted to people either by tick bites or through contact with infected animal blood or tissues during and immediately after slaughter. The majority of cases have occurred in people involved in the livestock industry, such as agricultural workers, slaughterhouse workers and veterinarians. Human-to-human transmission can occur resulting from close contact with the blood, secretions, organs or other bodily fluids of infected persons. Hospital-acquired infections can also occur due to improper sterilization of medical equipment, reuse of needles and contamination of medical supplies. Laboratory diagnosis of the infection during the acute phase of illness consists of detection of viral nucleic acid or or by demonstration of viral antigen by enzyme-linked immunoassay from serum or plasma samples. In samples collected later during the illness, diagnosis is confirmed by demonstration of specific IgG and IgM antibodies.;

ICD-11 synonym : Kara mikh typhoid fever; CCHF - [Crimean-Congo haemorrhagic fever]; Xīnjiāng hemorrhagic fever;

ICD-11 acronym : CCHF;

Details

Origin ID

1562906700;

UMLS CUI

C0019099;

Automatic exact mappings (from CISMeF team)
- Crimean-Congo hemorrhagic fever virus (organism) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Congo hemorrhagic fever (disorder) [SNOMED CT concept]
- Congo-Crimean Hemorrhagic Fever [NCIt concept]
- Congo-Crimean haemorrhagic fever [MedDRA Preferred Term]
- Congo-Crimean haemorrhagic fever [PASCAL descriptor]
- Congo-Crimean hemorrhagic fever [MedDRA LLT]
- Congo-Crimean hemorrhagic fever (disorder) [SNOMED CT concept]
- Crimean haemorrhagic fever [MedDRA LLT]
- Crimean hemorrhagic fever [MedDRA LLT]
- Crimean hemorrhagic fever [CHF Congo virus] [ICD-9 code]
- Crimean-Congo haemorrhagic fever [ICD-10 Sub-category (who)]
- Crimean-Congo hemorrhagic fever [ORDO Disease]
- Crimean-Congo hemorrhagic fever [ICD-10 Sub-category]
- congo-crimean hemorrhagic fever [SNOMED Notion]
- crimean haemorrhagic fever [Disease (Nov.)]
- hemorrhagic fever, crimean [MeSH concept]
- hemorrhagic fever, crimean [MeSH Descriptor]
ICD-10 Mapping
- Crimean-Congo hemorrhagic fever [ICD-10 Sub-category]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Congo hemorrhagic fever (disorder) [SNOMED CT concept]
- Congo-Crimean Hemorrhagic Fever [NCIt concept]
- Congo-Crimean haemorrhagic fever [MedDRA Preferred Term]
- Congo-Crimean haemorrhagic fever viral infection [MedDRA LLT]
- Congo-Crimean hemorrhagic fever [MedDRA LLT]
- Congo-Crimean hemorrhagic fever (disorder) [SNOMED CT concept]
- Congo-Crimean hemorrhagic fever viral infection [MedDRA LLT]
- Crimean haemorrhagic fever [MedDRA LLT]
- Crimean hemorrhagic fever [MedDRA LLT]
- Crimean hemorrhagic fever [CHF Congo virus] [ICD-9 code]
- Crimean-Congo hemorrhagic fever [DO Concept]
- Crimean-Congo hemorrhagic fever [ICD-10 Sub-category]
- Crimean-Congo hemorrhagic fever [ORDO Disease]
- congo-crimean hemorrhagic fever [SNOMED Notion]
- crimean haemorrhagic fever [Disease (Nov.)]
- hemorrhagic fever, crimean [MeSH Descriptor]
- hemorrhagic fever, crimean [MeSH concept]

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A disease caused by an infection with Crimean-Congo haemorrhagic fever virus. The length of the incubation period depends on the mode of acquisition of the virus. Following infection by a tick bite, the incubation period is usually one to three days, with a maximum of nine days. The incubation period following contact with infected blood or tissues is usually five to six days, with a documented maximum of 13 days. Onset of symptoms is sudden, with fever, myalgia, (muscle ache), dizziness, neck pain and stiffness, backache, headache, sore eyes and photophobia (sensitivity to light). There may be nausea, vomiting, diarrhoea, abdominal pain and sore throat early on, followed by sharp mood swings and confusion. After two to four days, the agitation may be replaced by sleepiness, depression and lassitude, and the abdominal pain may localize to the upper right quadrant, with detectable hepatomegaly (liver enlargement). Other clinical signs include tachycardia (fast heart rate), lymphadenopathy (enlarged lymph nodes), and a petechial rash (a rash caused by bleeding into the skin) on internal mucosal surfaces, such as in the mouth and throat, and on the skin. The petechiae may give way to larger rashes called ecchymoses, and other haemorrhagic phenomena. There is usually evidence of hepatitis, and severely ill patients may experience rapid kidney deterioration, sudden liver failure or pulmonary failure after the fifth day of illness. The mortality rate from CCHF is approximately 30%, with death occurring in the second week of illness. In patients who recover, improvement generally begins on the ninth or tenth day after the onset of illness. The CCHF virus is transmitted to people either by tick bites or through contact with infected animal blood or tissues during and immediately after slaughter. The majority of cases have occurred in people involved in the livestock industry, such as agricultural workers, slaughterhouse workers and veterinarians. Human-to-human transmission can occur resulting from close contact with the blood, secretions, organs or other bodily fluids of infected persons. Hospital-acquired infections can also occur due to improper sterilization of medical equipment, reuse of needles and contamination of medical supplies. Laboratory diagnosis of the infection during the acute phase of illness consists of detection of viral nucleic acid or or by demonstration of viral antigen by enzyme-linked immunoassay from serum or plasma samples. In samples collected later during the illness, diagnosis is confirmed by demonstration of specific IgG and IgM antibodies.