ICD-11 definition : Otosclerosis is a genetically mediated metabolic bone disease that affects the otic
capsule and stapes. It is an autosomal dominant disorder with varying penetrance and
expressivity. Usually symptomatic hearing loss from otosclerosis develops early in
the third decade of life, although onset in the teenage years does occur.;
Otosclerosis is a genetically mediated metabolic bone disease that affects the otic
capsule and stapes. It is an autosomal dominant disorder with varying penetrance and
expressivity. Usually symptomatic hearing loss from otosclerosis develops early in
the third decade of life, although onset in the teenage years does occur.