" /> Endemic non-venereal syphilis - CISMeF





ICD-11 code : 1C1F;

Preferred Label : Endemic non-venereal syphilis;

ICD-11 definition : Endemic non-venereal syphilis is caused by Treponema pallidum subspecies endemicum and is transmitted by skin-to-skin or mouth-to-mouth contact rather than sexual contact. Children are at greatest risk of infection. Clinical features are similar to venereal syphilis with a primary ulcer (usually in the mouth or on the nipples of breast-feeding women nursing infected children) and, in the secondary stage, a generalized papular rash, oral mucous patches, condylomata lata and generalized lymphadenopathy. Late stage infection is characterized by destructive gummata of the nasopharynx (gangosa), bones and skin.;

ICD-11 synonym : Belesh; Dichuchwa; Skerljevo; Frenga; Njovera; Endemic syphilis; Siti; Bejel;

ICD-11 inclusion : Bejel; Endemic syphilis; Njovera;

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Endemic non-venereal syphilis is caused by Treponema pallidum subspecies endemicum and is transmitted by skin-to-skin or mouth-to-mouth contact rather than sexual contact. Children are at greatest risk of infection. Clinical features are similar to venereal syphilis with a primary ulcer (usually in the mouth or on the nipples of breast-feeding women nursing infected children) and, in the secondary stage, a generalized papular rash, oral mucous patches, condylomata lata and generalized lymphadenopathy. Late stage infection is characterized by destructive gummata of the nasopharynx (gangosa), bones and skin.

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08/05/2025


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