ICD-11 code : L2-8C6;
Preferred Label : Myasthenia gravis or certain specified neuromuscular junction disorders;
ICD-11 definition : Myasthenia gravis is the most common autoimmune disease affecting the neuromuscular
junction and is characterised by painless fatigable muscle weakness. It is caused
by autoantibodies against neuromuscular junction proteins, either the nicotinic acetylcholine
receptor (AChR) or the muscle specific tyrosine kinase (MuSK). Mutations in neuromuscular
junction proteins cause congenital myasthenic syndromes. Other antibodies mediated
conditions affecting the neuromuscular junction, including Lambert Eaton myasthenic
syndrome and neuromyotonia.;
ICD-11 synonym : myasthenia gravis and other myoneural disorders;
ICD-11 inclusion : neuromuscular junction disorders;
ICD-11 "other" category code : 8C6Y;
ICD-11 "unspecified" category code : 8C6Z;
Origin ID : 1425591047;
Automatic exact mappings (from CISMeF team)
- ICD-10 Mapping
Myasthenia gravis is the most common autoimmune disease affecting the neuromuscular
junction and is characterised by painless fatigable muscle weakness. It is caused
by autoantibodies against neuromuscular junction proteins, either the nicotinic acetylcholine
receptor (AChR) or the muscle specific tyrosine kinase (MuSK). Mutations in neuromuscular
junction proteins cause congenital myasthenic syndromes. Other antibodies mediated
conditions affecting the neuromuscular junction, including Lambert Eaton myasthenic
syndrome and neuromyotonia.
