Preferred Label : Kaposi sarcoma;
Definition : A multicentric, malignant neoplastic vascular proliferation characterized by the development
of bluish-red cutaneous nodules, usually on the lower extremities, most often on the
toes or feet, and slowly increasing in size and number and spreading to more proximal
areas. The tumors have endothelium-lined channels and vascular spaces admixed with
variably sized aggregates of spindle-shaped cells, and often remain confined to the
skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's
sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United
States. An aggressive variant in young children is endemic in some areas of Africa.
A third form occurs in about 0.04% of kidney transplant patients. There is also a
high incidence in aids patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine,
3d ed, pp2105-7) hhv-8 is the suspected cause. [MeSH];
UMLS CUI (RADLEX) : C0036220;
Origin ID : RID3999;
UMLS CUI : C0036220;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
Semantic type(s)
UMLS correspondences (same concept)
A multicentric, malignant neoplastic vascular proliferation characterized by the development
of bluish-red cutaneous nodules, usually on the lower extremities, most often on the
toes or feet, and slowly increasing in size and number and spreading to more proximal
areas. The tumors have endothelium-lined channels and vascular spaces admixed with
variably sized aggregates of spindle-shaped cells, and often remain confined to the
skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's
sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United
States. An aggressive variant in young children is endemic in some areas of Africa.
A third form occurs in about 0.04% of kidney transplant patients. There is also a
high incidence in aids patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine,
3d ed, pp2105-7) hhv-8 is the suspected cause. [MeSH]